Synthesis of N-(2-SF5-ethyl)amines and impact of the SF5 substituent on their basicity and lipophilicity
Audrey Gilbert, Pauline Langowski, Jean‐François Paquin
Topics & Concepts
ChemistrySubstituentLipophilicityTrifluoromethanesulfonateSN2 reactionAmine gas treatingElectrophileMedicinal chemistrySulfanylOrganic chemistryCatalysisFluorine in Organic ChemistryClick Chemistry and ApplicationsChemical Reaction Mechanisms