Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach
Yi‐Hsien Cheng, Chunla He, Jim E. Riviere, Nancy A. Monteiro‐Riviere, Zhoumeng Lin
Abstract
< 0.01). We also demonstrate how PBPK modeling and simulation can be used as an effective tool to investigate tumor delivery efficiency of nanomedicines.
Topics & Concepts
Physiologically based pharmacokinetic modellingPharmacokineticsDrug deliveryNanomedicineNanoparticlePharmacologyMaterials scienceNanotechnologyMedicineNanoparticle-Based Drug DeliveryField-Flow Fractionation TechniquesRadiation Therapy and Dosimetry