Silent Mating–Type Information Regulation 2 Homolog 1 Attenuates the Neurotoxicity Associated with Alzheimer Disease via a Mechanism Which May Involve Regulation of Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-α
Yang‐Ting Dong, Kun Cao, Jie Xiang, Ling Shan, Zhi-Zhong Guan
Topics & Concepts
BiologyNeurotoxicityCoactivatorSirtuin 1NeuroprotectionSmall interfering RNASenile plaquesCell biologyReceptorTFAMMitochondrionApoptosisEndocrinologyAlzheimer's diseaseInternal medicineTransfectionMolecular biologyMitochondrial biogenesisPharmacologyDownregulation and upregulationBiochemistryMedicineTranscription factorToxicityGeneDiseaseSirtuins and Resveratrol in MedicineBiochemical effects in animalsNeuroscience and Neuropharmacology Research