YiQiFuMai Lyophilized Injection ameliorates tPA-induced hemorrhagic transformation by inhibiting cytoskeletal rearrangement associated with ROCK1 and NF-κB signaling pathways
Xuewei Pan, Meijuan Wang, Shuaishuai Gong, Minhui Sun, Yan Wang, Yuanyuan Zhang, Fang Li, Boyang Yu, Junping Kou
Topics & Concepts
Blood–brain barrierPharmacologyTissue plasminogen activatorIn vivoMedicineCofilinIschemiaReperfusion injuryIn vitroChemistryCytoskeletonInternal medicineBiologyBiochemistryActin cytoskeletonCellCentral nervous systemBiotechnologyBarrier Structure and Function StudiesProtease and Inhibitor MechanismsAcute Ischemic Stroke Management