Multiple cell types contribute to the atherosclerotic lesion fibrous cap by PDGFRβ and bioenergetic mechanisms
Alexandra Newman, Vlad Serbulea, Richard A. Baylis, Laura S. Shankman, Xenia Bradley, Gabriel F. Alencar, Katherine Owsiany, Rebecca A. Deaton, Santosh Karnewar, Sohel Shamsuzzaman, Anita Salamon, Mahima Reddy, Liang Guo, Aloke V. Finn, Renu Virmani, Olga A. Cherepanova, Gary K. Owens
Topics & Concepts
Fibrous capPDGFRBMural cellCell biologyPDGFBPlatelet-derived growth factor receptorMyofibroblastGrowth factorMesenchymal stem cellBiologyExtracellular matrixGrowth factor receptorCellCell typeReceptorPathologyIn vitroEndothelial stem cellSignal transductionMedicineFibrosisBiochemistryGeneAtherosclerosis and Cardiovascular DiseasesSingle-cell and spatial transcriptomicsAngiogenesis and VEGF in Cancer