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Design, synthesis, and biological evaluation of HDAC6 inhibitors targeting L1 loop and serine 531 residue

Sonam Jha, Ji Hyun Kim, Mikyung Kim, Ai-Han Nguyen, Khan Hashim Ali, Sunil Gupta, Sun You Park, Eunyoung Ha, Young Ho Seo

2023European Journal of Medicinal Chemistry14 citationsDOIOpen Access PDF

Topics & Concepts

HDAC6ChemistryAcetylationHistoneBiochemistryMicrotubule polymerizationMicrotubuleTubulinCell biologyHistone deacetylaseBiologyGeneHistone Deacetylase Inhibitors ResearchPeptidase Inhibition and AnalysisProtein Degradation and Inhibitors
Design, synthesis, and biological evaluation of HDAC6 inhibitors targeting L1 loop and serine 531 residue | Litcius