Tankyrase-selective inhibitor STP1002 shows preclinical antitumour efficacy without on-target toxicity in the gastrointestinal tract
Dong Young Kim, Young-Ju Kwon, Won Yong Seo, Uk–Il Kim, Seohyun Ahn, Seong Mi Choi, Hyung Tae Bang, Kyung‐Jin Kim, Jae‐Sung Kim
Topics & Concepts
Wnt signaling pathwayToxicityIn vivoPharmacologyColorectal cancerAdenomatous polyposis coliPharmacokineticsCancer researchMedicineCancerBiologySignal transductionInternal medicineBiochemistryBiotechnologyWnt/β-catenin signaling in development and cancerAldose Reductase and TaurineFibroblast Growth Factor Research