<i>In vivo</i> biodistribution of kinetically stable Pt<sub>2</sub>L<sub>4</sub> nanospheres that show anti-cancer activity
Eduard O. Bobylev, Renzo A. Knol, Simon Mathew, David A. Poole, Ioli Kotsogianni, Nathaniel I. Martin, Bas de Bruin, Alexander Kros, Joost N. H. Reek
Abstract
Two fluorescent, stable Pt 2 L 4 nanocages are developed. Pt 2 L 4 have alternated cytotoxicity and display diverse cell uptake in vivo making the versitale nanocages interesting candidates for further delivery and toxicity studies.
Topics & Concepts
NanocagesBiodistributionIn vivoCytotoxicityChemistryFluorescenceNanotechnologyCombinatorial chemistryIn vitroStereochemistryMaterials scienceBiochemistryCatalysisPhysicsBiotechnologyBiologyQuantum mechanicsNanocluster Synthesis and ApplicationsMetal complexes synthesis and propertiesSupramolecular Chemistry and Complexes