A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator
Jie Guo, Maojun Cheng, Peng Liu, Duanyuan Cao, Jinchong Luo, Yang Wan, Yuanying Fang, Yi Jin, Sai‐Sai Xie, Jing Liu
Topics & Concepts
ChemistryDimethyl fumaratePharmacologyActivator (genetics)NeuroprotectionTranilastInhibitory postsynaptic potentialBiochemistryStereochemistryReceptorNeuroscienceImmunologyBiologyMultiple sclerosisCholinesterase and Neurodegenerative DiseasesNuclear Receptors and SignalingSynthesis and biological activity