NAM protects against cisplatin-induced acute kidney injury by suppressing the PARP1/p53 pathway
Wenwen Wu, Ying Fu, Zhiwen Liu, Shaoqun Shu, Ying Wang, Chengyuan Tang, Juan Cai, Zheng Dong
Topics & Concepts
PARP1CisplatinAcute kidney injuryPoly ADP ribose polymeraseDNA damageNephrotoxicityApoptosisCancer researchPharmacologyChemistryProgrammed cell deathKidneyMedicinePolymeraseInternal medicineBiochemistryChemotherapyDNAChemotherapy-induced organ toxicity mitigationAcute Lymphoblastic Leukemia researchAcute Kidney Injury Research