Discovery of a CSF-1R inhibitor and PET tracer for imaging of microglia and macrophages in the brain
Berend van der Wildt, Jessica Klockow, Zheng Miao, Samantha T. Reyes, Jun Hyung Park, Bin Shen, Frederick T. Chin
Topics & Concepts
RadiosynthesisChemistryIn vivoMicrogliaEffluxIn vitroPharmacologyBlood–brain barrierReceptorBiochemistryMedicineInternal medicineCentral nervous systemBiologyInflammationBiotechnologyNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancerGlioma Diagnosis and Treatment