A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapies
Zhiwei Liu, Yingluo Liu, Lili Qian, Shangwen Jiang, Xiameng Gai, Shu Ye, Yuehong Chen, Xiaomin Wang, Linhui Zhai, Jun Xu, Congying Pu, Jing Li, Fuchu He, Min Huang, Minjia Tan
Topics & Concepts
PhosphoproteomicsKRASBiologyProteomicsProteomeComputational biologyCancerMutantTranscriptomeTargeted therapyBioinformaticsCancer researchKinaseGeneticsProtein phosphorylationProtein kinase AColorectal cancerGeneGene expressionPeptidase Inhibition and AnalysisProtein Kinase Regulation and GTPase SignalingUbiquitin and proteasome pathways