Peptide probes for proteases – innovations and applications for monitoring proteolytic activity
Maria Rodriguez-Rios, Alicia Megía-Fernández, Daniel J. Norman, Mark Bradley
Abstract
From a chemistry-based perspective, this review discusses the most recent advances in the field of substrate-based probes for the detection and analysis of proteolytic activity both in vitro and in vivo .
Topics & Concepts
ProteasesChemistryProteolytic enzymesSubstrate (aquarium)In vivoBiochemistryIn vitroComputational biologySubstrate specificityPeptideNanotechnologyCombinatorial chemistryBiologyEnzymeMaterials scienceBiotechnologyEcologyClick Chemistry and ApplicationsAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery