Water-soluble derivatives of evodiamine: Discovery of evodiamine-10-phosphate as an orally active antitumor lead compound
Shuqiang Chen, Kaijian Bi, Shanchao Wu, Yu Li, Yahui Huang, Chunquan Sheng, Guoqiang Dong
Topics & Concepts
EvodiamineChemistryIn vivoLead compoundPharmacologyApoptosisIn vitroCell cycle checkpointCell cultureCell growthCell cycleBiochemistryBiotechnologyChromatographyGeneticsMedicineBiologyCancer therapeutics and mechanismsQuinazolinone synthesis and applicationsSynthesis and biological activity