Case Report: Emergent Resistance in a Treatment-Naive Person With Human Immunodeficiency Virus Under Bictegravir-Based Therapy
Nicholas Chamberlain, Leandro Mena, James B. Brock
Abstract
Few instances of treatment-emergent resistance to bictegravir have been reported in the literature. We describe a case of treatment-emergent resistance to bictegravir in a person recently diagnosed with human immunodeficiency virus who developed M184V and R263K mutations while on therapy.
Topics & Concepts
MedicineResistance mutationHuman immunodeficiency virus (HIV)VirologyBiologyReverse transcriptaseBiochemistryRNAGeneHIV/AIDS drug development and treatmentHIV Research and TreatmentBiochemical and Molecular Research