Sulforaphane inhibits NLRP3 inflammasome activation in microglia through Nrf2-mediated miRNA alteration
Kemal Uğur Tüfekçi, İlkcan Ercan, Kamer Burak Isci, Melis Olcum, Bora Tastan, Ceren Perihan Gonul, Kursad Genc, Şermin Genç
Topics & Concepts
InflammasomePyroptosisMicrogliaCaspase 1Proinflammatory cytokineSecretionSulforaphaneCell biologyAIM2ChemistryNeuroinflammationGene silencingWestern blotBiologyImmunologyCancer researchInflammationBiochemistryGeneInflammasome and immune disordersIL-33, ST2, and ILC PathwaysGenomics, phytochemicals, and oxidative stress