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SARS-CoV-2 Seroprevalence among Healthcare, First Response, and Public Safety Personnel, Detroit Metropolitan Area, Michigan, USA, May–June 2020

Lara J. Akinbami, Nga Vuong, Lyle R. Petersen, Samira Sami, Anita Patel, Susan L. Lukacs, Lisa Mackey, Lisa A. Grohskopf, Amy Shehu, Jenny Atas

2020Emerging infectious diseases65 citationsDOIOpen Access PDF

Abstract

To estimate seroprevalence of severe acute respiratory syndrome 2 (SARS-CoV-2) among healthcare, first response, and public safety personnel, antibody testing was conducted in emergency medical service agencies and 27 hospitals in the Detroit, Michigan, USA, metropolitan area during May-June 2020. Of 16,403 participants, 6.9% had SARS-CoV-2 antibodies. In adjusted analyses, seropositivity was associated with exposure to SARS-CoV-2-positive household members (adjusted odds ratio [aOR] 6.18, 95% CI 4.81-7.93) and working within 15 km of Detroit (aOR 5.60, 95% CI 3.98-7.89). Nurse assistants (aOR 1.88, 95% CI 1.24-2.83) and nurses (aOR 1.52, 95% CI 1.18-1.95) had higher likelihood of seropositivity than physicians. Working in a hospital emergency department increased the likelihood of seropositivity (aOR 1.16, 95% CI 1.002-1.35). Consistently using N95 respirators (aOR 0.83, 95% CI 0.72-0.95) and surgical facemasks (aOR 0.86, 95% CI 0.75-0.98) decreased the likelihood of seropositivity.

Topics & Concepts

MedicineSeroprevalenceOdds ratioMetropolitan areaHealth carePublic healthEmergency departmentEmergency medicineFamily medicineDemographyEnvironmental healthInternal medicineImmunologySerologyAntibodyNursingPathologyEconomicsEconomic growthSociologySARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testingCOVID-19 Clinical Research Studies