RETRACTED ARTICLE: Dependence on linkers’ flexibility designed for benzenesulfonamides targeting discovery of novel hCA IX inhibitors as potent anticancer agents
Haytham O. Tawfik, Amany Belal, Mohammed A. S. Abourehab, Andrea Angeli, Alessandro Bonardi, Claudiu T. Supuran, Mervat H. El‐Hamamsy
Abstract
exposed constructive outcomes on normal cell lines, metastasis, and wound healing.Molecular docking and molecular dynamics (MDs) simulation was utilised to study binding mode.
Topics & Concepts
ChemistryDocking (animal)MoietyStereochemistryCell cycleApoptosisIC50Cell cultureIn vitroBiochemistryBiologyMedicineNursingGeneticsEnzyme function and inhibitionSynthesis and Catalytic ReactionsPhenothiazines and Benzothiazines Synthesis and Activities