The autotaxin-lysophosphatidic acid pathway mediates mesenchymal cell recruitment and fibrotic contraction in lung transplant fibrosis
Kenneth Sinclair, Stephanie T. Yerkovich, Peter Hopkins, Ann Fieuw, Paul Ford, Joseph E. Powell, Brendan O’Sullivan, Daniel C. Chambers
Topics & Concepts
Mesenchymal stem cellLungAutotaxinLysophosphatidic acidFibrosisLung transplantationBronchoalveolar lavageStromal cellProgenitor cellMedicinePathologyImmunologyBiologyInternal medicineStem cellCell biologyReceptorSphingolipid Metabolism and SignalingInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisTransplantation: Methods and Outcomes