Propargyl Chalcones’ Radical Annulation/Sulfonation Reaction: Efficient Synthesis of Benzo[<i>b</i>]oxepin-5(2<i>H</i>)-one and Chromane Derivatives
Qiuyu Yu, Jinghang Zhang, Jinghang Zhang, Fan Wu, Xiaoqin Liu, Chang Wang, Jinpeng Zhang, Jinpeng Zhang, Liangce Rong
Abstract
]oxepinone and chromane derivatives was reported by the reaction of propargyl chalcones with arylsulfonyl chloride via radical cascade annulation/sulfonation under laboratory conditions. Readily available propargyl chalcones, commercialized arylsulfonyl chloride, and simple reaction conditions make this six(seven)-membered oxygen-containing heterocycles' synthetic strategy more attractive and with significant application values.
Topics & Concepts
AnnulationChemistryPropargylChlorideMedicinal chemistryOrganic chemistryCatalysisSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsOrganoselenium and organotellurium chemistry