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The Pangenome: A Data-Driven Discovery in Biology

Duccio Medini, Claudio Donati, Rino Rappuoli, Hervé Tettelin

202023 citationsDOIOpen Access PDF

Abstract

Abstract An early example of Big data in biology: how a mathematical model, developed to address a practical question in vaccinology, transformed established concepts, opening biology to the “unbounded.”

Topics & Concepts

BiologyComputational biologyEvolutionary biologyEvolution and Genetic Dynamicsvaccines and immunoinformatics approachesGenetics, Bioinformatics, and Biomedical Research
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