Palladium-Catalyzed Regioselective Arylation of Unprotected Allylamines
Vinod G. Landge, Justin M. Maxwell, Pratibha Chand-Thakuri, Mohit Kapoor, Evan Diemler, Michael C. Young
Abstract
precatalyst. Key features of the method are the ability to access relatively mild conditions that facilitate a broad substrate scope as well as direct diarylation of terminal allylamine substrates. In addition, several complex and therapeutically relevant molecules are included to demonstrate the utility of the transformation.
Topics & Concepts
Amine gas treatingAllylamineRegioselectivityCatalysisPalladiumCombinatorial chemistryChemistrySubstrate (aquarium)Organic chemistryScope (computer science)Computer scienceBiologyEcologyPolymerPolyelectrolyteProgramming languageCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsAsymmetric Hydrogenation and Catalysis