Enantioselective catalytic remote perfluoroalkylation of α-branched enals driven by light
Matteo Balletti, Tommy Wachsmuth, Antonio Di Sabato, Will C. Hartley, Paolo Melchiorre
Abstract
-4-hydroxy-l-proline, secures a consistently high stereocontrol while inferring complete site selectivity for the more distal γ position of the dienamines.
Topics & Concepts
MoietyChemistryEnantioselective synthesisTrifluoromethylOrganocatalysisPhotochemistryCombinatorial chemistryElectron transferRadicalAcceptorCatalysisSelectivityStereochemistryOrganic chemistryAlkylPhysicsCondensed matter physicsFluorine in Organic ChemistryRadical Photochemical ReactionsCatalytic C–H Functionalization Methods