Activatable UCL/CT/MR-enhanced <i>in vivo</i> imaging-guided radiotherapy and photothermal therapy
Jianming Ni, Huiting Xu, Yanqi Zhong, Yongping Zhou, Shudong Hu
Abstract
in tumors and cause an abundant generation of oxygen for hypoxic improvement, leading to an enhanced RT. More importantly, by irradiation with near-infrared light, the scattered CuS NPs can convert light energy into heat to destroy tumor cells and reinforce the therapeutic effects of RT. Furthermore, these NPs also displayed excellent performances in upconversion fluorescence imaging (UCL), computerized tomographic (CT) scanning and magnetic resonance imaging (MRI), demonstrating a potential imaging-guided cancer therapy system.
Topics & Concepts
Photothermal therapyMaterials scienceMagnetic resonance imagingRadiation therapyIn vivoNanoparticleBiomedical engineeringNanotechnologyCancer researchMedicineRadiologyBiologyBiotechnologyNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsCancer, Stress, Anesthesia, and Immune Response