Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics
Annette M. Vogl, Lilian Phu, Raquel Becerra, Sebastián A. Giusti, Erik Verschueren, Trent Hinkle, Martín D. Bordenave, Max Adrian, Amy Heidersbach, Patricio Yankilevich, Fernando D. Stefani, Wolfgang Wurst, Casper C. Hoogenraad, Donald S. Kirkpatrick, Damián Refojo, Morgan Sheng
Topics & Concepts
NeddylationNEDD8CullinUbiquitinCell biologyNeuriteBiologyCOP9 signalosomeActinATG8CofilinCytoskeletonActin cytoskeletonBiochemistryUbiquitin ligaseAutophagyProteaseEnzymeCellPeptide HydrolasesIn vitroGeneApoptosisUbiquitin and proteasome pathwaysPeptidase Inhibition and AnalysisGenetic Neurodegenerative Diseases