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Piperlongumine conjugates induce targeted protein degradation

Jing Pei, Yufeng Xiao, Xingui Liu, Wanyi Hu, Amin Sobh, Yaxia Yuan, Shuo Zhou, Nan Hua, Samuel G. Mackintosh, Xuan Zhang, Kari B. Basso, Manasi Kamat, Qingping Yang, Jonathan D. Licht, Guangrong Zheng, Daohong Zhou, Dongwen Lv

2023Cell chemical biology71 citationsDOIOpen Access PDF

Topics & Concepts

Ubiquitin ligaseUbiquitinDNA ligaseProtein degradationProteolysisChemistryBiochemistryProteasomeUbiquitin-Protein LigasesCell biologyBiologyMolecular biologyDNAEnzymeGeneProtein Degradation and InhibitorsPeptidase Inhibition and AnalysisHistone Deacetylase Inhibitors Research