Pathogenic variants in actionable MODY genes are associated with type 2 diabetes
Amélie Bonnefond, Mathilde Boissel, Alexandre Bolze, Emmanuelle Durand, Bénédicte Toussaint, Emmanuel Vaillant, Stefan Gaget, Franck De Graeve, Aurélie Dechaume, Frédéric Allegaert, David Le Guilcher, Loïc Yengo, Véronique Dhennin, Jean-Michel Borys, James T. Lu, Elizabeth T. Cirulli, Gai Elhanan, Ronan Roussel, Beverley Balkau, Michel Marre, Sylvia Franc, G. Charpentier, Martine Vaxillaire, Mickaël Canouil, Nicole Washington, Joseph J. Grzymski, Philippe Froguel
Topics & Concepts
HNF1BType 2 diabetesGeneticsPrecision medicineHNF1AGeneDiabetes mellitusMaturity onset diabetes of the youngBiologyGenome-wide association studyBioinformaticsMedicineMutationSingle-nucleotide polymorphismGenotypeEndocrinologyHomeoboxGene expressionPancreatic function and diabetesGenetics and Neurodevelopmental DisordersCancer-related gene regulation