Curcumin as a Natural Therapeutic Agent: A Rapid Review of Potential Clinical Uses and Mechanisms of Action
Mohammad Mohajeri, Reza Momenai, Somayyeh Karami‐Mohajeri, Mandana Ohadi, Mohammad Amin Raeisi Estabragh
Abstract
Context: Curcumin, a natural compound derived from the rhizome of the turmeric plant, exhibits various pharmacological and therapeutic effects through distinct cellular and molecular mechanisms. Evidence Acquisition: Given the therapeutic applications and pharmacological properties of curcumin, it is essential to explore its pharmacological effects for potential use in clinical research. Notably, curcumin demonstrates significant antioxidant, anti-inflammatory, and anti-cancer properties. Importantly, no side effects or specific toxicity have been reported for curcumin. Results: Curcumin, as a natural compound, can be utilized as a drug supplement in treatment regimens for various diseases. Numerous clinical studies have indicated that curcumin enhances the efficacy of chemotherapy drugs or mitigates their side effects when used concurrently. Conclusions: This review presents an overview of studies conducted on the pharmacological effects and therapeutic properties of curcumin.