Enhanced Carboxymethyl Cellulose-Based Hydrogels for Wound Dressings
Nannan Zhong, Ning Cao, Ziyang Cheng, Shangshang Fang, Ming Jiang, Jing Guan, Wenbo Wang, Xiaobei Zang
Abstract
The development of ideal wound dressings with superior properties represents a critical demand in wound management. In recent years, carboxymethyl cellulose (CMC) has garnered significant attention as a high-value material for biomedical applications. Due to its exceptional biocompatibility, low toxicity, and functional versatility, carboxymethyl cellulose has emerged as a promising candidate for developing hydrogel-based wound dressings. This review systematically examines the potential of carboxymethyl cellulose and carboxymethyl cellulose-derived hydrogel dressings as advanced wound care solutions, emphasizing advancements in performance metrics and multifunctional applications, including self-healing capabilities, pH responsiveness, and sustained drug release. Furthermore, we comprehensively summarize recent progress in carboxymethyl cellulose-based hydrogel biomaterials for wound dressing applications and propose strategic prospects for future development to enhance the clinical translation of CMC hydrogel systems.