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Impeding the Medical Protective Clothing Contamination by a Spray Coating of Trifunctional Polymers

Hyeongseop Keum, Dohyeon Kim, Chang‐Hee Whang, Aram Kang, Seojung Lee, Woonsung Na, Sangyong Jon

2022ACS Omega17 citationsDOIOpen Access PDF

Abstract

, a typical pathogenic bacterium that induces an upper respiratory infection. Regardless of the molar ratio, polymer-coated PPE surfaces showed considerable antiadhesion (∼65-75%) and antibacterial (∼75-87%) efficacies soon after being in contact with pathogens and maintained their capability for at least 24 h, which is sufficient for disposable PPEs. Further antiviral tests using coronaviruses showed favorable results with PPE coated at two specific ratios (3.5:6:0.5 and 3.5:5.5:1) of poly(DMA-PEGMA-QA). Moreover, biocompatibility assessments using the two most effective polymer ratios showed no recognizable local or systemic inflammatory responses in mice, suggesting the potential of this polymer for immediate use in the field.

Topics & Concepts

BiofoulingMethacrylateCoatingPolymerContext (archaeology)Ethylene glycolBiocompatibilityContaminationAntimicrobialMaterials scienceChemistryNanotechnologyMonomerComposite materialOrganic chemistryMembraneBiologyBiochemistryPaleontologyEcologyAntimicrobial agents and applicationsInfection Control and VentilationInfection Control in Healthcare