Sphincter-saving surgery after neoadjuvant therapy for ultra-low rectal cancer where abdominoperineal resection was indicated: 10-year results of the GRECCAR 1 trial
Philippe Rouanet, Michel Rivoire, Sophie Gourgou, Bernard Lelong, Éric Rullier, Mehrdad Jafari, Laurent Mineur, Marc Pocard, Jean‐Luc Faucheron, F. Dravet, Denis Pezet, Jean‐Michel Fabre, L. Bresler, Jacques Balosso, C. Lemanski
Abstract
This phase III trial included patients with ultra-low rectal adenocarcinoma that initially required abdominoperineal resection. The surgical decision was based on clinical tumour status after preoperative treatment. The overall sphincter-saving resection rate was 85 per cent, with 72 per cent rate of intersphincteric resection. Long-term results showed that changing the initial abdominoperineal resection indication into a sphincter-saving resection according to tumoral response is oncologically safe. Saving the sphincter