Insights into the secondary and tertiary structure of the Bovine Viral Diarrhea Virus Internal Ribosome Entry Site
Devadatta Gosavi, Iwona K. Wower, Irene K. Beckmann, Ivo L. Hofacker, Jacek Wower, Michael T. Wolfinger, Joanna Sztuba-Solińska
Abstract
species. These studies provide detailed insight into the structural arrangement of BVDV IRES RNA H-type pseudoknot and encompassing motifs that likely contribute to the optimal functionality of viral cap-independent translation element.
Topics & Concepts
PseudoknotInternal ribosome entry siteBiologyRNANucleic acid structureComputational biologyVirologyIn silicoRibosomeTranslation (biology)Protein tertiary structureProtein secondary structureGeneticsGeneMessenger RNABiochemistryAnimal Disease Management and EpidemiologyViral Infections and Immunology ResearchRNA and protein synthesis mechanisms