Heart Repair: Injection of ROS‐Responsive Hydrogel Loaded with Basic Fibroblast Growth Factor into the Pericardial Cavity for Heart Repair (Adv. Funct. Mater. 15/2021)
Zhenhua Li, Dashuai Zhu, Hui Qi, Jianing Bi, Bingjie Yu, Zhen Huang, Shiqi Hu, Zhenzhen Wang, Thomas G. Caranasos, Joseph S. Rossi, Xiaokun Li, Ke Cheng, Xiaojie Wang
Abstract
In article number 2004377, Ke Cheng, Xiaojie Wang, and co-workers fabricate a fibroblast growth factor (FGF)-loaded and reactive oxygen species (ROS)-responsive hydrogel for intrapericardial delivery. The safety and feasibility of minimally invasive injection and access into the pericardial cavity in both pigs and human patients are also demonstrated.
Topics & Concepts
Materials sciencePericardial cavityFibroblastFibroblast growth factorBiomedical engineeringReactive oxygen speciesPericardial windowPericardiumCancer researchCell biologyCardiologyMedicineInternal medicineChemistryBiologyBiochemistryIn vitroReceptorTissue Engineering and Regenerative Medicine