Fabrication of a hierarchical nanoreactor based on COFs for cascade enzyme catalysis
Xiaolian Yang, Zheng Tan, Hanjun Sun, Yushi Tong, Xiao‐Chun Huang, Junying Ren, Chen Wang, Weiyang Shen
Abstract
A hierarchical nanoreactor based on covalent organic frameworks (COFs) was fabricated using polystyrene spheres (PSs) as a template. When applied in cascade catalysis, the nanoreactor significantly improved the catalytic activity of internal enzymes, and showed protection for the enzyme in harsh environments. Moreover, glucose can be sensitively detected (detection sensitivity: 10 μM) by the nanoreactor.
Topics & Concepts
NanoreactorCascadeCatalysisArtificial enzymeCovalent bondFabricationPolystyreneNanotechnologyChemistryCascade reactionEnzymeImmobilized enzymeMaterials scienceChemical engineeringCombinatorial chemistryOrganic chemistryChromatographyPolymerEngineeringMedicinePathologyAlternative medicineCovalent Organic Framework ApplicationsMetal-Organic Frameworks: Synthesis and ApplicationsElectrochemical sensors and biosensors