Synthesis and biological evaluation of all possible inosine-mixed cyclic dinucleotides that activate different hSTING variants
Zhenghua Wang, Can-Can Zhao, Chuanlin Wang, Hang Zhang, Dejun Ma, Qiangzhe Zhang, Xin Wen, Luyuan Li, Zhen Xi
Topics & Concepts
ChemistryInosineStereochemistryBiochemistryComputational biologyCombinatorial chemistryEnzymeBiologyinterferon and immune responsesRNA modifications and cancerViral Infections and Vectors