Light activation of cyclometalated ruthenium complexes drives towards caspase 3 dependent apoptosis in gastric cancer cells
Jorge Andrés Solís-Ruiz, Anaïs Barthe, Gilles Riegel, Rafael Omar Saavedra-Díaz, Christian Gaiddon, Ronan Le Lagadec
Topics & Concepts
RutheniumChemistryApoptosisSinglet oxygenCytotoxicityCancer cellReactive oxygen speciesMode of actionCisplatinIC50In vitroBiophysicsIn vivoCaspaseProgrammed cell deathBiochemistryCancerOxygenCatalysisBiologyBiotechnologyChemotherapyGeneticsOrganic chemistryMetal complexes synthesis and propertiesFerrocene Chemistry and ApplicationsSynthesis and Biological Evaluation