Host Genetics and Environment Shape the Composition of the Gastrointestinal Microbiome in Nonhuman Primates
Jacob K. Flynn, Alexandra M. Ortiz, Richard Herbert, Jason M. Brenchley
Abstract
Our data point to the degree to which host genetics can influence GI microbiome composition and suggest, within primate species, that individual host genetics is unlikely to significantly alter the microbiome. These data are important for the development of therapeutics aimed at altering the microbiome within populations of genetically disparate members of primate species.
Topics & Concepts
MicrobiomeBiologyHost (biology)Evolutionary biologyNonhuman primatePrimateMicrobial geneticsGut microbiomeGeneticsEcologyGeneGut microbiota and healthClostridium difficile and Clostridium perfringens researchProbiotics and Fermented Foods