Litcius/Paper detail

Squalene epoxidase/SQLE is a candidate target for treatment of colorectal cancers with <i>p53</i> mutation and elevated c-<i>MYC</i> expression

Yuyun Du, Matjaž Rokavec, Heiko Hermeking

2023International Journal of Biological Sciences16 citationsDOIOpen Access PDF

Abstract

inactivation and elevated c-MYC activity.

Topics & Concepts

Squalene monooxygenaseCancer researchBiologyTranscription factorGeneMolecular biologyGeneticsBiosynthesisCancer, Lipids, and MetabolismUbiquitin and proteasome pathwaysRNA Research and Splicing