Emergence of Novel Norovirus GII.4 Variant
Preeti Chhabra, Damien C. Tully, Janet Mans, Sandra Niendorf, Leslie Barclay, Jennifer L. Cannon, Anna Montmayeur, Chao‐Yang Pan, Nicola Page, Rachel Williams, Helena J. Tutill, Sunando Roy, Cristina Celma, Stuart Beard, Michael L. Mallory, Gédéon Prince Manouana, Thirumalaisamy P. Velavan, Ayôla Akim Adégnika, Peter G. Kremsner, Lisa C. Lindesmith, Stéphane Hué, Ralph S. Baric, Judith Breuer, Jan Vinjé
Abstract
We detected a novel GII.4 variant with an amino acid insertion at the start of epitope A in viral protein 1 of noroviruses from the United States, Gabon, South Africa, and the United Kingdom collected during 2017-2022. Early identification of GII.4 variants is crucial for assessing pandemic potential and informing vaccine development.
Topics & Concepts
NorovirusVirologyPandemicEpitopeBiologyIdentification (biology)Coronavirus disease 2019 (COVID-19)GeneticsVirusMedicineAntibodyDiseaseBotanyPathologyInfectious disease (medical specialty)Viral gastroenteritis research and epidemiologyRespiratory viral infections researchAnimal Virus Infections Studies