Enantioselective direct, base-free hydrogenation of ketones by a manganese amido complex of a homochiral, unsymmetrical P–N–P′ ligand
Chris S. G. Seo, Brian T. H. Tsui, Matthew V. Gradiski, Samantha A. M. Smith, Robert H. Morris
Abstract
Base-free direct hydrogenation of ketones using a Mn(PNP′)(CO)<sub>2</sub> complex is more enantioselective than that of a related base-activated iron complex.
Topics & Concepts
Enantioselective synthesisManganeseLigand (biochemistry)ChemistryCatalysisBase (topology)Free baseAsymmetric hydrogenationStereochemistryCombinatorial chemistryOrganic chemistryReceptorBiochemistryMathematicsMathematical analysisSalt (chemistry)Asymmetric Hydrogenation and CatalysisSurface Chemistry and CatalysisCatalysis for Biomass Conversion