Combined Photoredox and Iron Catalysis for the Cyclotrimerization of Alkynes
Michael Neumeier, Uttam Chakraborty, Dieter Schaarschmidt, Víctor A. de la Peña O’Shea, Raúl Pérez–Ruíz, Axel Jacobi von Wangelin
Abstract
Abstract Successful combinations of visible‐light photocatalysis with metal catalysis have recently enabled the development of hitherto unknown chemical reactions. Dual mechanisms from merging metal‐free photocatalysts and earth‐abundant metal catalysts are still in their infancy. We report a photo‐organo‐iron‐catalyzed cyclotrimerization of alkynes by photoredox activation of a ligand‐free Fe catalyst. The reaction operates under very mild conditions (visible light, 20 °C, 1 h) with 1–2 mol % loading of the three catalysts (dye, amine, FeCl 2 ).
Topics & Concepts
Photoredox catalysisChemistryCatalysisCombinatorial chemistryOrganic chemistryPhotocatalysisRadical Photochemical ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods