A study of the mechanism of small-molecule soybean-protein-derived peptide supplement to promote sleep in a mouse model
Guofu Yi, Bushra Safdar, Yihao Zhang, You Li, Xinqi Liu
Abstract
SBP doubled the 5-HT content in the brain and promoted an awake state. As a result, the produced 5-HT could not be converted into MT in large amounts, so the sleep duration was shorter than that of the control group. These findings suggested the potential of using SBP in appropriate amounts as functional ingredients in various food products to improve sleep in elderly people afflicted with sleep disorders.
Topics & Concepts
MelatoninSerotoninSleep (system call)5-HT receptorEndocrinologyTryptophanInternal medicinePeptideReceptorChemistryPharmacologyBiochemistryMedicineAmino acidComputer scienceOperating systemBiochemical effects in animalsSleep and related disordersObesity, Physical Activity, Diet