Two-photon excitable membrane targeting polyphenolic carbon dots for long-term imaging and pH-responsive chemotherapeutic drug delivery for synergistic tumor therapy
Sayan Deb Dutta, Jin Hexiu, Jongsung Kim, Sourav Sarkar, Jagannath Mondal, Jeong Man An, Yong-Kyu Lee, Md Moniruzzaman, Ki‐Taek Lim
Abstract
-CQDs@Dox complex has higher affinity towards tumor cells, better inhibitory effects, and an absence of systemic toxicity. Therefore, our developed nanocarrier exhibited better cell imaging, drug delivery, and tumor-targeting properties, and could be used as a "smart" probe for synergistic tumor therapy.
Topics & Concepts
ChemistryDrug deliveryMembraneDrugTwo-photon excitation microscopyBiophysicsDrug carrierNanotechnologyPharmacologyBiochemistryMaterials scienceMedicineFluorescenceBiologyOrganic chemistryPhysicsQuantum mechanicsCarbon and Quantum Dots ApplicationsAdvanced biosensing and bioanalysis techniquesNanoplatforms for cancer theranostics