Litcius/Paper detail

Biological formation of ethylene

Robert P. Hausinger, Simahudeen Bathir Jaber Sathik Rifayee, Midhun George Thomas, Shramana Chatterjee, Jian Hu, Christo Christov

2023RSC Chemical Biology20 citationsDOIOpen Access PDF

Abstract

, and water. Despite catalyzing distinct chemical reactions, EFE and ACCO are related in sequence and structure, and both enzymes require Fe(ii) for their activity. Advances in our understanding of EFE, derived from both experimental and computational approaches, have clarified how this enzyme catalyzes its dual reactions. Drawing on the published mechanistic studies of ACCO and noting the parallels between this enzyme and EFE, we propose a novel reaction mechanism for ACCO.

Topics & Concepts

EthyleneChemistryCarboxylateEnzymeBiochemistryBiophysicsBiologyCatalysisEnzyme Catalysis and ImmobilizationPolyamine Metabolism and ApplicationsPhotosynthetic Processes and Mechanisms