Systematic mapping of R-group space enables the generation of an R-group replacement system for medicinal chemistry
Kosuke Takeuchi, Ryo Kunimoto, Jürgen Bajorath
Topics & Concepts
ChemistryGroup (periodic table)Chemical spaceStereochemistryCombinatorial chemistryOrganic chemistryDrug discoveryBiochemistryChemical Synthesis and AnalysisComputational Drug Discovery MethodsAnalytical Chemistry and Chromatography