The Role of β-Glycosylated Wall Teichoic Acids in the Reduction of Vancomycin Susceptibility in Vancomycin-Intermediate Staphylococcus aureus
Michael Hort, Ute Bertsche, Senada Nožinović, Alina Dietrich, Anne Sophie Schrötter, Laura Mildenberger, Katharina Axtmann, Anne Berscheid, Gabriele Bierbaum
Abstract
acetyl-d-glucosamine in a closely related isolate through the induction of salt stress, we could show that the β-conformation of the sugars plays a vital role in the resistance of S. aureus VC40.
Topics & Concepts
Teichoic acidStaphylococcus aureusAutolysinVancomycinPeptidoglycanMicrobiologyAutolysis (biology)Glycopeptide antibioticCell wallTeicoplaninChemistryStaphylococcal infectionsBiologyBiochemistryBacteriaEnzymeGeneticsAntimicrobial Resistance in StaphylococcusBiochemical and Structural CharacterizationBacterial Genetics and Biotechnology