MAFG-driven osteosarcoma cell progression is inhibited by a novel miRNA miR-4660
Huajian Shan, Lun‐qing Zhu, Chen Yao, Zhi-qing Zhang, Yuan-yuan Liu, Qin Jiang, Xiaozhong Zhou, Xiaodong Wang, Cong Cao
Abstract
growth in proximal tibia of the nude mice. In summary, MAFG overexpression-driven OS cell progression is inhibited by miR-4660. The miR-4660-MAFG axis could be novel therapeutic target for human OS.
Topics & Concepts
microRNAOsteosarcomaBiologyCancer researchCellCell cycle progressionCell biologyComputational biologyGeneticsGeneCell cycleMicroRNA in disease regulationCircular RNAs in diseasesCancer-related molecular mechanisms research