An update on small molecule compounds targeting synthetic lethality for cancer therapy
Jiaxiang Luo, Yang Li, Yiwen Zhang, Defa Wu, Yijiu Ren, Jie Liu, Chengdi Wang, Jifa Zhang, Jifa Zhang
Topics & Concepts
ChemistrySynthetic lethalityLethalitySmall moleculeCancer therapyCancerCombinatorial chemistryStereochemistryComputational biologyBiochemistryToxicologyDNA repairInternal medicineDNAMedicineBiologyPARP inhibition in cancer therapyCancer-related Molecular PathwaysProtein Degradation and Inhibitors