Albumin grafted coaxial electrosparyed polycaprolactone-zinc oxide nanoparticle for sustained release and activity enhanced antibacterial drug delivery
W. P. T. D. Perera, Ranga Dissanayake, Janitha M. Unagolla, Rangika T. De Silva, Sanjaya D. N. K. Bathige, Lakshitha Pahalagedara
Abstract
lung deposition study showed 70% of APCL-CLOX-ZnO particles can reach up to the alveoli level. Therefore, this novel coaxial nanoformulation may serve as a promising drug delivery platform for the treatment of bacterial infections including respiratory tract complications.
Topics & Concepts
PolycaprolactoneCloxacillinNanoparticleZincDrug deliveryMaterials scienceChemical engineeringChemistryNanotechnologyPolymerComposite materialMetallurgyAntibioticsPenicillinEngineeringBiochemistryElectrohydrodynamics and Fluid DynamicsNanoparticles: synthesis and applicationsNanoparticle-Based Drug Delivery