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Systems Genetics in Human Endothelial Cells Identifies Non-coding Variants Modifying Enhancers, Expression, and Complex Disease Traits

Lindsey K. Stolze, Austin C. Conklin, Michael B. Whalen, Maykel López Rodríguez, Kadri Õunap, Ilakya Selvarajan, Anu Toropainen, Tiit Örd, Jin Li, Anna Eshghi, Alice E Solomon, Yun Fang, Minna U. Kaikkonen, Casey E. Romanoski

2020The American Journal of Human Genetics55 citationsDOIOpen Access PDF

Topics & Concepts

BiologyEnhancerExpression quantitative trait lociGeneticsEpigenomicsEpigeneticsPhenotypeQuantitative trait locusSingle-nucleotide polymorphismGenome-wide association studyGeneComputational biologyAlleleRegulation of gene expressionTranscription factorGene expressionDNA methylationGenotypeCongenital heart defects researchGenetic Associations and EpidemiologyUbiquitin and proteasome pathways
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